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NEET Biology: Molecular Basis of Inheritance. Chapter-wise Practice Questions and Test

Molecular Basis of Inheritance is a Class 12 Biology chapter that carries about 6.2% of the Biology questions in NEET. Practise it with 73 questions covering 7 topics, each with an explanation.

Practise Molecular Basis of Inheritance

Sets of 15 questions that adapt to your level, with an explanation for every answer.

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Topics covered in Molecular Basis of Inheritance

How often Molecular Basis of Inheritance has come up in NEET

Across the 13 previous year papers, Molecular Basis of Inheritance had 71 questions, about 5.5 a year. The most in one paper was 9, in NEET 2021.

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Sample questions on Molecular Basis of Inheritance with answers

8 questions from the practice bank, spread across the chapter's topics. The full set is in the app.

Question 1: DNA Replication

Okazaki fragments are short DNA segments formed during:

  1. A Transcription
  2. B Translation
  3. C DNA replication
  4. D DNA repair

Answer: C. DNA replication

Why: Because DNA polymerase synthesizes only in the 5'→3' direction, the lagging strand is replicated discontinuously in short segments called Okazaki fragments, later joined by DNA ligase.

Question 2: DNA Structure and Packaging

A nucleosome consists of about 200 base pairs of DNA wound around:

  1. A a non-histone protein
  2. B a histone octamer of H1 only
  3. C a histone octamer, with two molecules each of H2A, H2B, H3 and H4
  4. D an RNA molecule

Answer: C. a histone octamer, with two molecules each of H2A, H2B, H3 and H4

Why: Histone H1 binds the linker DNA between nucleosomes.

Question 3: Gene Expression Regulation (Lac Operon)

In the lac operon, the gene i codes for:

  1. A permease
  2. B the repressor protein
  3. C β-galactosidase
  4. D RNA polymerase

Answer: B. the repressor protein

Why: The repressor binds to the operator.

Question 4: Genetic Code

H. G. Khorana contributed to the cracking of the genetic code by:

  1. A discovering DNA
  2. B finding reverse transcriptase
  3. C isolating ribosomes
  4. D chemically synthesising RNA molecules with defined repeating sequences

Answer: D. chemically synthesising RNA molecules with defined repeating sequences

Why: He used them to find which amino acids each codon specified.

Question 5: Human Genome Project and DNA Fingerprinting

The Human Genome Project aimed to determine:

  1. A the complete sequence of the 3 × 10⁹ base pairs of the human genome
  2. B the structure of proteins only
  3. C the number of chromosomes only
  4. D the age of humans

Answer: A. the complete sequence of the 3 × 10⁹ base pairs of the human genome

Why: The project was completed in 2003.

Question 6: Transcription

The strand of DNA that has the same base sequence as the mRNA (with T in place of U) is the:

  1. A Okazaki strand
  2. B primer
  3. C template strand
  4. D coding (non-template) strand

Answer: D. coding (non-template) strand

Why: The template strand is read by the RNA polymerase.

Question 7: Translation

A polysome (polyribosome) is:

  1. A a collection of nucleosomes
  2. B a group of ribosomes attached to a single mRNA
  3. C a ribosome with many tRNAs
  4. D a group of mRNAs on one ribosome

Answer: B. a group of ribosomes attached to a single mRNA

Why: It allows many copies of the polypeptide to be made at the same time.

Question 8: DNA Replication

The strand of DNA that is synthesised continuously during replication is the:

  1. A leading strand
  2. B lagging strand
  3. C template strand only
  4. D coding strand only

Answer: A. leading strand

Why: The lagging strand is made as Okazaki fragments.

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Frequently asked questions

How many questions come from Molecular Basis of Inheritance in NEET?

Molecular Basis of Inheritance carries about 6.2% of the Biology questions in NEET. Across the 13 previous year papers on NeetVictory it appeared 71 times, about 5.5 questions a year.

Which class is Molecular Basis of Inheritance from?

Molecular Basis of Inheritance is a Class 12 Biology chapter in the NCERT syllabus.

Where can I practise Molecular Basis of Inheritance questions for NEET?

NeetVictory has 73 practice questions on Molecular Basis of Inheritance, each with an explanation, in sets of 15 that adapt to your level. This page shows a free sample.

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